Stages of Mitosis Simple Notes
Definition of Mitosis:
It is a type of cell division that results in two genetically
identical daughter cells, each with the same number of chromosomes as the
parent cell.
You can watch our 3 minute video here Stages of mitosis
- Growth
- Tissue repair or wound healing
- Asexual reproduction in organisms like budding in hydra and yeast.
Mitosis
is divided into 4 stages such as prophase, metaphase, anaphase, and telophase.
Stage 1: Prophase
- Chromosomes condense and when stained it is visible with two identical chromatids called sister chromatids that are joined together at the centromere
- The two centrosomes (replicated in the G2 phase just before prophase) move towards opposite poles.
- Spindle fibres made up of protein microtubules starts to emerge from the centrosomes (which consist of two centrioles in animal cells)
- The nuclear membrane breaks down into small vesicles
Stage 2: Metaphase
- Chromosomes line up at the equator of the spindle (also known as the metaphase plate)
- Centrosomes reach opposite poles
- Spindle fibres attaches to the centromeres of the chromosome
- Each sister chromatid is attached to a spindle fibre originating from opposite poles
Stage 3: Anaphase
- The sister chromatids are pulled apart at the centromere and move toward opposite poles of the cell.
- Spindle fibres begin to shorten.
- This separation ensures that each new daughter cell will receive an identical set of chromosomes
Stage 4: Telophase
- Chromosomes arrive at opposite poles and begin to decondense back into chromatin
- Nuclear envelopes begin to reform around each set of chromosomes
- The spindle fibres break down.
During
cytokinesis, the cytoplasm divides, resulting in two separate daughter cells,
each with a complete set of chromosomes and its own nucleus.
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