Is Glycolysis partial oxidation? How RBC gets energy? Why glycolysis is known as common pathway?

 Why Glycolysis is known as universal, ancient pathway?

Cellular respiration is a catabolic process which involves the intracellular oxidation of glucose or organic molecules through series of enzymatic reaction producing energy in the form of ATP with the release of CO2 and H2O as byproducts.

Glycolysis (Glyco=Glucose; lysis= splitting) is the oxidation of glucose (C 6) to 2 pyruvate (3 C) with the formation of ATP and NADH.

Glycolysis is a universal anerobic pathway happening in all organisms: aerobic, anerobic or facultative organisms from bacteria to yeast to mammals.

As the site of glycolysis is cytosol of the cytoplasm, literally all organisms including prokaryotes can carry out glycolysis.

As it is a universal pathway, most biologists consider it to be the most fundamental and primitive pathway for making ATP.

Is Glycolysis partial oxidation?

Is Glycolysis aerobic or anaerobic?

Glycolysis is a 10-step process that forms ATP where oxygen is not involved, therefore anaerobic.

Watch 10 steps of glycolysis

Is Glycolysis a partial oxidation of Glucose?

In Glycolysis, Glucose undergoes partial oxidation in glycolysis; to form two molecules of pyruvic acid along with formation of 2 ATP and NADH. Here 6 carbon glucose splits to form two 3 carbon pyruvate which can be further oxidised via Krebs cycle and Electron transport chain in aerobic cellular reparation.

Complete oxidation of glucose to CO2 and H2O in aerobic respiration yields approximately 36-38 ATP molecules

Why is Glycolysis also known as EMP pathway?

EMP stands for Embden, Meyerhof, and Parnas; Who discovered the most common type of glycolytic pathway occurring in majority of organisms.

Other pathways, such as the Entner–Doudoroff pathway occurs in some Gram negative bacteria only.

How RBC get energy without mitochondria?

In RBC, nucleus, mitochondria or cell organelles are absent. RBC obtain their energy using glycolysis to produce ATP. Even though RBCs carry oxygen, but cannot use oxygen as it lacks mitochondrion for aerobic cellular respiration. In RBC, ATP is produced by means of fermentation, via glycolysis of glucose and by lactic acid production.

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