Cancer: It is a group of disorders resulting from a loss of cell cycle control due to multiple mutational events.
Or It is a group of diseases characterized by uncontrolled cell growth and division.
Characteristics of cancer cells:
Other characters:
Density independent growth of cells: Normal cells stop division when it touches the boundaries of other cells, termed as ‘contact inhibition’. Cancer cells loss this property and form layers one above the other.
Altered morphology: The nucleus of the cells become irregular and the number of lysosomes increase in cancer cells.
Stay away from smoking, drugs and alcohol…..
Reference: http://www.cancer.gov/cancertopics/
Or It is a group of diseases characterized by uncontrolled cell growth and division.
Characteristics of cancer cells:
- Uncontrolled cell growth and division. (Cells becomes immortal)
- Cells become independent from normal cellular controls that limits growth and division.
- It becomes invasive or capable of spreading from one tissues to other called as metastasis.
Other characters:
- Reduced cell-to cell interaction.
- Failure of differentiation: Cell division without differentiation.
- Failure of apoptosis or programmed cell death.
- Production of collagenase, a protease for metastasize.
- Uncontrolled division even in the absence of growth stimulators (immortal).
- Presence of telomerase in cancer cells.
- Cells show aneuploids or variation in chromosome number.
- Cancer cell induces vascularization to support their growth.
- Induce angiogenesis (blood vessel formation).
Stay away from smoking, drugs and alcohol…..
Reference: http://www.cancer.gov/cancertopics/
Tags:
Cancer
Cancer biology
cell cycle
Cell differentiation
cell division
Characteristics of cancer cells
oncology