Comparison of B and T cells involved in Immune Response (B cells vs Tcells)

Lymphocytes are mononucleate, nongranular leukocytes of lymphoid tissue, participating in immunity. They are found in blood, lymph and lymphoid  tissues such as spleen, lymph nodes, tonsils, Peyer’s patches, appendix. etc. The lymphocytes are of two types. They are B lymphocytes and T lymphocytes.

Comparison of B and T cells:

Property	B cells	T cells
Origin	Bone marrow in adults	Bone marrow in adults
Maturation	Lymphoid tissue or bone marrow; Bursa of Fabricius in birds	Thymus
Longevity	Short (Few days to a week)	Long (Months to years)
Complement receptors	Present	Absent
Surface immunoglobulins	Present	Absent
Proliferation	Proliferate upon antigenic stimulation, differentiate into plasma and memory cells	Proliferate upon antigenic stimulation
Type of immunity	Humoral immunity	Cell mediated and humoral
Secretary product	Antibodies	Lymphokines
Distribution	High in spleen, lymph nodes, bone marrow and other lymphoid tissues, Low in blood	High in blood, lymph and lymphoid tissue
Types and Functions	Memory cells- along lived cell responsible for the anamnestic response. Plasma cell- a cell arising from a B cell that manufactures specific antibodies	Tc Cell- Lysis cells recognised as non self and parasite infected cells. TH cell- It is necessary for B cell activation by T-dependent antigens and T effector cell. T regulator cell- It develops into TH or Ts cells and control balance between enhancement and suppression of response to antigen. Ts cell: It blocks induction  and or/ activation of TH cells and B cells. It helps maintain tolerance. TDTH cell: It provides protection against infectious agents, mediates inflammation and activates macrophages in delayed type hypersensitivity Null cells- Lymphocytes that lacks surface cell markers