It is a collection of mechanism within an organism that
protects against diseases by identifying
and killing pathogens and tumor cells.It detects a wide variety of
agents from viruses to parasitic worms, and needs to distinguish them from the
organism’s own healthy cells and tissues in order to function properly.The
immune system of vertebrae such as human consists of many types of proteins
(immunoglobulins), cells, organs and tissues, which interact in an
elaborate and dynamic network (world of immunity).
Parts of the Immune system
The human immune system comprises lymphoid organs , tissue cells
and soluble molecules such as antibodies. Lymphoid organs are
those organs where the maturation and proliferation of lymphocytes
takes place.
There are two types of lymphoid organs :primary lymphoid organs and
secondary lymphoid organs.
Primary lymphoid organs (Central Lymphoid organs)
are those organs T
lymphocytes and B lymphocytes mature and acquire
their antigen specific receptors. Thymus and Bursa of Fabricus of birds are
primary lymphoid organs.
The bone marrow of mammals is considered equivalent to avian Bursa of Fabricius. Bone marrow is the main lymphoid organ where all blood cells including lymphocytes are formed. Thymus is the site of T lymphocyte maturation and bone marrow is the site of B lymphocytes maturation and are responsible for cellular and humoral immune response respectively.
The bone marrow of mammals is considered equivalent to avian Bursa of Fabricius. Bone marrow is the main lymphoid organ where all blood cells including lymphocytes are formed. Thymus is the site of T lymphocyte maturation and bone marrow is the site of B lymphocytes maturation and are responsible for cellular and humoral immune response respectively.
Secondary Lymphoid organs (Peripheral Lymphoid organs) are lymphnodes, spleen, tonsils,
Peyer's patches of the small intestine, appendix and mucousal associated
lymphoid tissue (MALT).
After the maturation, B
lymphocytes and T lymphocytes migrate via blood vascular system and lymphatic
system to the secondary lymphoid organs where they undergo proliferation and
differentiation.
Tags:
appendix
bone marrow
Central Lymphoid organs
Lymphnodes
MALT
mucousal associated lymphoid tissue
Peyer's patches of the small intestine
Primary lymphoid organs
spleen
Thymus
tonsils